Protect Your Kidneys - Control Diabetes
In 2010, our fifth World Kidney Day focussed on diabetes,
the most common cause of kidney failure.
www.worldkidneyday.org or info@worldkidneyday.org
Healthy Weight: Healthy Blood Pressure
In partnership with World Kidney Day
May 17 2010
World Hypertension League manages
World Hypertension Day
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World Kidney Day Editorial 2010
Diabetic kidney disease: Act now or pay later English
Enfrmedad Renal Diabética: Actúe ahora o pague luego Spanish
Robert C Atkins and Paul Zimmet on behalf of 2010 International Society of Nephrology/International Federation of Kidney Foundations, World Kidney Day Steering Committee* (RA) and International Diabetes Federation (PZ) November 2009.
General facts on Chronic Kidney Disease (CKD)
COMMON
More than 5% of the adult population have some form of kidney damage, and every year millions die prematurely of cardiovascular diseases linked to Chronic Kidney Diseases (CKD).
HARMFUL
Common causes of CKD include inflammatory diseases of the kidney, infections, obstruction in the urinary tract and inherited disorders like polycystic kidney disease. But in both developed and developing nations diabetes and hypertension are becoming the most common causes of CKD, especially in older people. These are also the most common causes of cardiovascular disease (CVD).
The first consequence of undetected CKD is the risk of developing progressive loss of kidney function leading to kidney failure and the need for dialysis treatment or a kidney transplant. The second is premature death from associated cardiovascular disease. Individuals who appear to be healthy who are then found to have CKD have an increased risk of dying prematurely from CVD (coronary disease, cerebrovascular disease, peripheral artery disease, and heart failure) regardless of whether they ever develop kidney failure. Current Global Snapshot of CKD - Kidney disease is very common, it affects an increasing number of people and cultures from continent to continent. It is estimated that approximately 400-600 million adults worldwide have chronic kidney disease. It is a harmful. The first consequence of undetected CKD is the risk of developing progressive loss of kidney function leading to kidney failure and the need for dialysis treatment or a kidney transplant to maintain life. The second is premature death from associated cardiovascular disease. Most importantly, most forms of kidney disease are treatable, its progression can often be curtailed particularly if caught early. Early detection and treatment can often keep chronic kidney disease from getting worse, and can prevent the need for dialysis or a transplant.
TREATABLE
Detection - Kidney disease can be detected early. Simple laboratory tests are done on small samples of blood (to measure creatinine content and estimate GFR) and on urine (to measure creatinine and albumin excretion). The majority of individuals with early stages of CKD go undiagnosed, particularly in the developing world. The early detection of kidney impairment is essential and allows suitable treatment before kidney damage or cardiovascular problems occur.
Screening - Screening must be a priority for those people considered to be at high risk of kidney disease, namely:
* Patients with diabetes mellitus and hypertension
* Individuals who are obese or smoke
* Individuals over 50 years of age
* Individuals with a family history of kidney disease, diabetes mellitus or hypertension
Chronic, non-communicable diseases and CKD - Chronic health conditions such as cardiovascular disease, hypertension, diabetes mellitus and chronic kidney disease have now replaced the communicable diseases as the leading threat to public health and health budgets worldwide. Deaths claimed by infectious diseases will decline by 3% over the next decade. In marked contrast, chronic diseases – that already account for 72% of the total global burden of disease in people over 30 – will increase by 17%. Much of this in developing countries.
The cost of treating these chronic diseases, already 80% of many health care budgets, represents a leading threat to public health and healthcare resources worldwide. The only feasible global response to this pending health and socio-economic crisis is chronic disease prevention. Promoting early detection and prevention of CKD will be an important step towards achieving the World Health Organization (WHO) recommended goal of reducing death rates related to chronic disease in the world by 2% per year over the next decade.
Key preventative measures - The seven golden rules to note for prevention of CKD, defined and proven successful in protecting against both renal and cardiovascular disease:
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Reduction of high blood pressure - the lower the blood pressure, the slower the GFR decline
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Specific medications to reduce proteinuria as well as lower blood pressure - ACE inhibitors/ARBs
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Reduce salt intake to lower blood pressure
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Control of glucose, blood lipids and anemia
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Stop smoking
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Increased physical activity
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Control of body weight
Treatment - Clinical research over the last decade has shown the potential benefit of blockade of the renin-angiotensin system by ACEs and ARBs to significantly reduce the burden of disease from CVD, diabetes, hypertension and CKD at relatively low cost.
World Kidney Day Secretariat
Rue du Luxembourg 22-24, B-1000 Brussels, Belgium
Ph +322 213 13 63 * Fx +322 213 13 13
www.worldkidneyday.org or info@worldkidneyday.org
IFKF Global Headquarters
PO Box 2020, 1400 DA, Bussum Netherlands
Ph +31 35 697 8010 Fx +31 35 697 8080
Jan Lantink - IFKF Special Project Director
lantink@nwq.nl
Marie-Agnès Cederborg - Project Manager
marie-agnes.cederborg@interel.eu
Joint initiative of 
and 
Updated 10 June 2010